When picking or editing a gaming or anime PFP, focus on a clear silhouette and...

https://chloessuperthoughts.quantlynix.com/posts/why-do-bold-cartoon-faces-read-better-than-realistic-art-in-tiny-icons

When picking or editing a gaming or anime PFP, focus on a clear silhouette and crop close to the face for easy recognition. Keep the background simple and avoid text to prevent clutter